ELISA-VIDITEST anti-complement factor H is intended for the quantitative detection of IgG antibodies against human complement factor H in human serum or plasma.

Factor H is a complement regulatory glycoprotein that is found in human plasma in concentrations of 300 – 800 mg/L. Autoantibodies that inhibit factor H function cause complement dysregulation and they have been detected in about 10% of patients with atypical hemolytic uremic syndrome (aHUS). Atypical HUS is a clinical syndrom that is characterised by microangiopatic hemolytic anemia, thrombocytopenia and renal failure.